Βιβλιογραφία Χολοκυστεκτομή

Cholocystectomy and cancers

Xiong J, Wang Y, Huang H, Bian J, Wang A, Long J, Zheng Y, Sang X, Xu Y, Lu X, Zhao H. Systematic review and meta-analysis: cholecystectomy and the risk of cholangiocarcinoma. Oncotarget. 2017 Jul 26;8(35):59648-59657. doi: 10.18632/oncotarget.19570. PMID: 28938668; PMCID: PMC5601764.

Kim, Y.A., Kim, H., Kang, M.J. et al. Increased diagnosis of hepato-biliary-pancreatic cancer after cholecystectomy: a population-based study. Sci Rep 15, 411 (2025). https://doi.org/10.1038/s41598-024-84781-7

Choi YJ, Jin EH, Lim JH, Shin CM, Kim N, Han K, Lee DH. Increased Risk of Cancer after Cholecystectomy: A Nationwide Cohort Study in Korea including 123,295 Patients. Gut Liver. 2022 May 15;16(3):465-473. doi: 10.5009/gnl210009. PMID: 35502586; PMCID: PMC9099388.

Gallstones, Cholecystectomy and the Risk of

Hepatobiliary and Pancreatic Cancer: A Nationwide

Population-based Cohort Study in Korea, Dan Huang 2020

Sun M, Ma T, Yuan H

Association between history of cholecystectomy and risk of gastric cancer: a meta-analysis of epidemiological studiesBMJOpen 2023;13:e057138. doi: 10.1136/bmjopen-2021-057138

Cholocystectomy and Alzheimer's:

Gu H, Yu K, Zhou J, et al. Perturbations in lipid metabolism mediate the relationship between cholecystectomy and dementia: A mediation Mendelian randomization study. Journal of Alzheimer’s Disease. 2025;0(0). doi:10.1177/13872877251376316

Cholocystectomy and Gut Dysbiosis and Metabolic Syndrome:

Xu F, Chen R, Zhang C, Wang H, Ding Z, Yu L, Tian F, Chen W, Zhou Y, Zhai Q. Cholecystectomy Significantly Alters Gut Microbiota Homeostasis and Metabolic Profiles: A Cross-Sectional Study. Nutrients. 2023 Oct 17;15(20):4399. doi: 10.3390/nu15204399. PMID: 37892474; PMCID: PMC10609985.

Di Ciaula A, Garruti G, Wang DQ, Portincasa P. Cholecystectomy and risk of metabolic syndrome. Eur J Intern Med. 2018 Jul;53:3-11. doi: 10.1016/j.ejim.2018.04.019. Epub 2018 Apr 26. PMID: 29706426; PMCID: PMC8118133.

Bile Acids and Vitamins A, D, E, k deficiency.

Vitamin A deficiency and vision:

Ali Saeed, Mark Hoekstra, Martijn Oscar Hoeke, Janette Heegsma, Klaas Nico Faber, The interrelationship between bile acid and vitamin A homeostasis, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Volume 1862, Issue 5, 2017, Pages 496-512, ISSN 1388-1981, https://doi.org/10.1016/j.bbalip.2017.01.007

Vitamin D deficiency

Polat HB, Beyazal MS. The effect of cholecystectomy on 25-hydroxyvitamin D levels and bone mineral density in postmenopausal women. Arch Osteoporos. 2018 May 22;13(1):61. doi: 10.1007/s11657-018-0458-0. PMID: 29790021.

https://www.drrpadmakumar.com/blog/vitamin-d-deficiency-surgeon-perspective/

Stoker GE, Buchowski JM, Stoker ME. Prior Cholecystectomy as a Predictor of Preoperative Vitamin D Deficiency in Adults Undergoing Spine Surgery. Arch Surg. 2012;147(6):577–578. doi:10.1001/archsurg.2012.463

Cholocystectomy and fractures:

Lee Eun Ji , Shin Cheol Min , Lee Dong Ho , Han Kyungdo , Park Sang Hyun , Kim Yoo Jin , Yoon Hyuk , Park Young Soo , Kim Nayoung. The Association Between Cholecystectomy and the Risk for Fracture: A Nationwide Population-Based Cohort Study in Korea Frontiers in Endocrinology Volume 12 - 2021 2021 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.657488 DOI:10.3389/fendo.2021.657488 ISSN:1664-2392

Cholocystectomy and type 2 diabetes

Huh JH, Lee KJ, Cho YK, Moon S, Kim YJ, Roh E, Han KD, Koh DH, Kang JG, Lee SJ, Ihm SH. Cholecystectomy Increases the Risk of Type 2 Diabetes in the Korean Population: Data From the National Health Insurance Cooperation Health Checkup 2010-2017. Ann Surg. 2023 Aug 1;278(2):e264-e271. doi: 10.1097/SLA.0000000000005683. Epub 2022 Sep 5. PMID: 36066197.

Cholocystectomy and fatty liver disease

Ruhl CE, Everhart JE. Relationship of non-alcoholic fatty liver disease with cholecystectomy in the US population. Am J Gastroenterol. 2013 Jun;108(6):952-8. doi: 10.1038/ajg.2013.70. Epub 2013 Apr 2. PMID: 23545713.

Kwak MS, Kim D, Chung GE, Kim W, Kim YJ, Yoon JH. Cholecystectomy is independently associated with nonalcoholic fatty liver disease in an Asian population. World J Gastroenterol. 2015 May 28;21(20):6287-95. doi: 10.3748/wjg.v21.i20.6287. PMID: 26034364; PMCID: PMC4445106.

Cholocystectomy and cardiovascular disease

Chavez-Tapia NC, Kinney-Novelo IM, Sifuentes-Rentería SE, Torres-Zavala M, Castro-Gastelum G, Sánchez-Lara K, Paulin-Saucedo C, Uribe M, Méndez-Sánchez N. Association between cholecystectomy for gallstone disease and risk factors for cardiovascular disease. Ann Hepatol. 2012 Jan-Feb;11(1):85-9. PMID: 22166565.